The standard procedures for sizing the spaces for passenger activities in airport terminals are unsatisfactory in that they easily lead to expensive errors. The essential difficulty lies in the nature of the process, and in particular with the several formulas which specify the area per passenger in different parts of the building. The process and these formulas are insensitive both to the vari...

The autotransporters comprise a functionally diverse family of gram-negative proteins that mediate their own export across the bacterial outer membrane. They consist of an amino-terminal passenger region called the "alpha-domain" and the structural hallmark of the autotransporter family, a carboxy-terminal transporter region usually referred to as the "beta-domain." The passenger region can be ...

today, due to rising passenger expectations and other resource constraints, the airport managers and staff do to develop appropriate programs in order to optimize the allocation of the resources. gates and counters are important resources in airport. in this research problem of gate and counter for arrival flights is considered simultaneously and mathematical model is prepared. the objectives o...

Autotransporters are bacterial virulence factors consisting of an N-terminal "passenger domain" that is secreted in a C- to-N-terminal direction and a C-terminal "β domain" that resides in the outer membrane (OM). Although passenger domain secretion does not appear to use ATP, the energy source for this reaction is unknown. Here, we show that efficient secretion of the passenger domain of the E...

Autotransporters are a superfamily of virulence factors produced by Gram-negative bacteria consisting of a large N-terminal extracellular domain ("passenger domain") and a C-terminal beta barrel domain ("beta domain"). The mechanism by which the passenger domain is translocated across the outer membrane (OM) is unknown. Here we show that the insertion of a small linker into the passenger domain...

Many of the virulence determinants secreted from pathogenic Gram-negative bacteria are autotransporter proteins, which are usually either exported to the bacterial cell surface or secreted into the external environment. There appears to be dearth of information regarding the exact mechanism of their processing into the surface-exposed passenger domains and C-terminal, βdomains. The C-terminal p...

This paper deals with how to develop a model to forecast air passenger demand and to evaluate some policy scenarios related with runway and passenger terminal capacity expansion to meet the future demand. System dynamics frameworks can be used to model, to analyze and to generate scenario to increase the system performance because of its capability of representing physical and information flows...

Autotransporters are a superfamily of virulence factors produced by Gram-negative bacteria that are comprised of an N-terminal extracellular domain (passenger domain) and a C-terminal β barrel domain (β domain) that resides in the outer membrane (OM). The β domain promotes the translocation of the passenger domain across the OM by an unknown mechanism. Available evidence indicates that an α-hel...

MicroRNA duplices are separated into a guide and a passenger strand. By convention, the guide represents the active microRNA while the passenger is supposedly degraded. However, passenger strands also emerge as active microRNAs. It is unknown whether the guide-to-passenger-strand ratio can be actively regulated and which factors influence strand incorporation into the RISC. Here, we identify a ...

Autotransporters are bacterial virulence factors that share a common mechanism by which they are transported to the cell surface. They consist of an N-terminal passenger domain and a C-terminal β-barrel, which has been implicated in translocation of the passenger across the outer membrane (OM). The mechanism of passenger translocation and folding is still unclear but involves a conserved region...